中文:牛磺酸去氧胆酸
中文同义词: 牛磺脱氧胆酸;牛熊去氧胆酸钠;牛磺酸熊脱氧胆酸;牛磺熊脱氧胆酸钠盐;牛磺酸熊去脱氧胆酸;牛磺熊脱氧胆酸;牛磺雄去氧胆酸;牛磺熊去氧胆酸
英文名称: TAUROURSODEOXYCHOLIC ACID
英文同义词: 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-(2-SULFOETHYL)AMIDE;TAUROURSODEOXYCHOLIC ACID;TAUROURSODESOXYCHOLIC ACID;2-(((3-alpha,5-beta,7-beta)-3,7-dihydroxy-24-oxocholan-24-ethanesulfonicaci;2-(((3-alpha,5-beta,7-beta)-3,7-dihydroxy-24-oxocholan-24-yl)amino)ethanesul;fonicacid;n-(3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oyl)-taurin;ur906
CAS号: 14605-22-2
分子式: C26H45NO6S
分子量: 499.7
EINECS号:
相关类别: 中草药成分;Miscellaneous Natural Products;Bile Acids;Biochemistry;Steroids;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;中药对照品;Herb extract;对照品、标准品;生化试剂;其它试剂;原料药;植物提取物;对照品;胆酸系列;医药原料药;标准品
Mol文件: 14605-22-2.mol

牛熊去氧胆酸钠 性质
熔点 173-175°C
折射率 46 ° (C=1, EtOH)
CAS 数据库 14605-22-2(CAS DataBase Reference)

牛熊去氧胆酸钠 用途与合成方法
药物作用及临床应用 牛熊去氧胆酸钠又称牛磺熊去氧胆酸、牛磺熊脱氧胆酸，化学名称为3α，7β二羟基胆烷酰-N-牛磺酸，主要是存在于黑熊胆汁中，是熊胆中标志性有效成分。具有解痉、抗惊厥、抗炎及溶胆石等作用。
现代合成药物牛磺熊去氧胆酸，是由熊去氧胆酸的梭基与牛磺酸的氨基之间缩水而成的结合型胆汁酸。国外牛磺熊去氧胆酸胶囊已经上市，2007年作为进口药品获准在中国销售，临床主要用于治疗胆囊胆固醇结石、原发硬化性胆管炎、原发胆汁性肝硬化和慢性丙型病毒性肝炎等。目前牛磺熊去氧胆酸原料药及其制剂在中国还没有药品注册。
牛熊去氧胆酸钠是从熊胆汁中分离出来一种天然胆汁酸，属化学制剂，在体内与牛磺酸结合存在于胆汁中，是一种亲水性胆酸，为一种胆固醇结石溶解剂。能减少肝脏对胆固醇的分泌，降低胆汁中胆固醇的饱和度，促进胆汁酸的分泌，增加胆固醇在胆汁中的溶解度，使胆固醇结石溶解或防止结石的形成。可增加胆汁分泌量，松弛胆管口括约肌产生利胆作用，有利于结石的排出。本品不能溶解其他类型的胆结石。适用于治疗胆固醇性结石、高脂血症、胆汁分泌障碍性疾病、原发性胆汁性肝硬化、慢性肝炎、胆汁反流性胃炎和预防肝移植急性排斥及反应。本品的溶石作用略弱于鹅去氧胆酸。
以上信息由Chemicalbook的Andy编辑整理。
含量：98%以上
是否合成：是（有天然提取）
包装：1kg铝箔袋 5kg纸板桶

Chinese: ursodeoxycholic acid taurine
Chinese Synonyms: taurodeoxycholic acid; CBBC sodium deoxycholate; ursodeoxycholic acid taurine; tauro ursodeoxycholic acid sodium salt; taurine bear to deoxycholate; tauro ursodeoxycholic acid; taurocholic male deoxycholate; tauroursodeoxycholic acid
English name: TAUROURSODEOXYCHOLIC ACID
English Synonyms: 3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N- (2-SULFOETHYL) AMIDE; TAUROURSODEOXYCHOLIC ACID; TAUROURSODESOXYCHOLIC ACID; 2 - (((3-alpha, 5-beta, 7-beta) - 3,7-dihydroxy-24-oxocholan-24-ethanesulfonicaci; 2 - (((3-alpha, 5-beta, 7-beta) -3,7-dihydroxy-24-oxocholan-24-yl) amino) ethanesul; fonicacid; n- (3-alpha, 7-beta-dihydroxy-5-beta-cholan-24-oyl) -taurin; ur906
CAS: 14605-22-2
Formula: C26H45NO6S
Molecular weight: 499.7
EINECS:
Related Categories: herbal ingredients; Miscellaneous Natural Products; Bile Acids; Biochemistry; Steroids; Chiral Reagents; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; medicine reference substance; Herb extract; Controls, Standards; biochemical reagents; other reagents; APIs ; plant extracts; reference; acid series; pharmaceutical raw materials; standard
Mol File: 14605-22-2.mol

CBBC sodium deoxycholate nature
Melting point of 173-175 ° C
Refractive index of 46 ° (C = 1, EtOH)
CAS databases 14605-22-2 (CAS DataBase Reference)

CBBC sodium deoxycholate Usage And Synthesis
CBBC drug action and clinical application, also known as sodium deoxycholate tauroursodeoxycholic acid, taurocholic ursodeoxycholic acid, the chemical name for 3α, 7β-dihydroxy-bile alkanoylthio -N- taurine, mainly exist in black bear bile, is the active ingredient in bear bile iconic. Has antispasmodic, anti-convulsants, anti-inflammatory and dissolve gallstones and so on.
Modern synthetic drugs tauroursodeoxycholic acid, is a shuttle between ursodeoxycholic acid and taurine amino group formed by shrinking conjugated bile acids. Foreign tauroursodeoxycholic acid capsule has been listed in 2007 as import drugs approved for sale in China, mainly for the treatment of cholesterol gallstones, primary sclerosing cholangitis, primary biliary cirrhosis and chronic hepatitis C virus hepatitis. Currently API tauroursodeoxycholic acid and its preparations in China yet registered medicines.
CBBC sodium deoxycholate is separated from the bear bile out of a natural bile acid, is a chemical in the body combined with taurine is present in the bile, is a hydrophilic bile acid, as a cholesterol gallstones solubilizer. Can reduce the secretion of cholesterol in the liver, reducing the saturation of bile cholesterol, promote the secretion of bile acids, increases the solubility of cholesterol in the bile, cholesterol stones dissolve or prevent stone formation. Increase the secretion of bile, bile duct mouth sphincter relaxation produced choleretic effect, conducive to the discharge of stones. This product can not dissolve other types of gallstones. For the treatment of cholesterol stones, hyperlipidemia, bile secretion disorders, primary biliary cirrhosis, chronic hepatitis, bile reflux gastritis and prevention of acute rejection in liver transplantation and reactions. RONGSHI effect of this product is slightly weaker than chenodeoxycholic acid.
The above information is edited by Chemicalbook of Andy.
Content: 98% or more
Whether synthesis: is (a natural extract)
Packaging: 1kg aluminum foil bag 5kg cardboard

Sales guide price: 8600 / kg